Clinical Effectiveness of Pre-treatment with Chlorhexidine in Adhesive Dental Restorations. Systematic Review and Meta-analysis.

Objective: To determine, by means of a systematic review and meta-analysis, the clinical effectiveness pre-treatment with chlorhexidine (CHX) in adhesive dental restorations. Material Methods: A literature search was conducted until February 2020, biomedical databases: Pubmed, Embase, Scielo, Science Direct, Scopus, SIGLE, LILACS, Google Scholar Cochrane Central Registry Clinical Trials. The selection criteria studies were defined, which were: randomized controlled trials, without language time restrictions, reporting effects (retention, marginal discoloration, adaptation, postoperative sensitivity secondary caries) pre-CHX treatment Study risk bias analyzed using Handbook Systematic Reviews Interventions. Results: strategy resulted six articles five entered meta-analysis. reported that there no difference retention, sensitivity, caries from CHX Conclusion: reviewed suggests pretreatment does not influence